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Why does one Vitamin C product perform differently from another?

By Becca Robertson

A new systematic review published in the Journal of Clinical and Aesthetic Dermatology highlights an important point: when it comes to Vitamin C, formulation matters.

Rather than simply looking at whether a product contains Vitamin C, the review found that factors such as the Vitamin C derivative, formulation, stability and delivery system all influence clinical performance.

The review also discusses lipophilic Vitamin C derivatives, including Tetrahexyldecyl Ascorbate (THDA) and Ascorbyl Tetraisopalmitate (ATIP), for their role in supporting healthy-looking skin.
Revision Skincare's C+ Correcting Complex 30%® is formulated with THD Ascorbate, reflecting the brand's commitment to advanced formulation science.

The full publication is available in the Revision Skincare® Client Resources under Clinical Studies as "Vitamin C in Dermatology – Systematic Review (JCAD, 2026)". You can also access it HERE

We encourage you to explore this and our growing library of peer-reviewed research supporting the science behind Revision Skincare® products.