The Science is Black and White
Disruptive Innovation, True Visible Results™.
At Revision Skincare® our mission is to challenge the status quo through pioneering innovation. Our dedication to rigorous clinical testing, modelled on pharmaceutical protocols, places us at the forefront of medical-grade professional skincare.
We never compromise, and neither should you.
Unique Benefits
Our mission is that every product delivers benefits you can see for yourself, whether as part of a rejuvenating regimen or an enhancement to in-clinic procedures.
Proven Science
Disruptive Innovation
Award Winning
Synergistic Usage
True Visible Results
The Science
Innovative Formulas Deliver True Visible Results.
Our superior formulation philosophy is driven by an unwavering passion to deliver transformative results, while simultaneously promoting and protecting the microbiome and overall skin health.
The Proof
Medical-Grade Clinical Excellence Is Why Revision Skincare® Is The Choice of Medical Professionals.
We guarantee the efficacy of our innovative technologies and formulas by holding ourselves to the highest standards of clinical excellence, conducting rigorous, conclusive testing validated by physicians.
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Frequently Asked Questions
THD Ascorbate is an ester of Vitamin C that permeates the skin and is converted to ascorbic acid in the skin by esterase. This theory is supported by several tests including using a 3D skin model to perform an evaluation of a formulation containing 10% THD Ascorbate.
The stratum corneum of the 3D skin model was treated for a 48 hour period and a HPLC analysis was then performed. The results show that the formulation containing THD Ascorbate penetrated and was converted to ascorbic acid in the 3D skin model.
(Ochiai Y, Kaburagi S, Obayashi K, et al. A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. J Dermatol Sci. 2006;44(1):37-44.)
Another test shows that THD Ascorbate permeates the hydrophobic plasma membrane and is converted to ascorbic acid in NHDF fibroblasts. The test was conducted in parallel with ascorbic acid and THD Ascorbate enhanced intracellular ascorbic acid levels more so than ascorbic acid itself. It is assumed that the accumulation of ascorbic acid occurred through esterolytic conversion of the THD Ascorbate.
(Xiao L, Kaneyasu K, Saitoh Y, Terashima Y, Kowata Y, Miwa N. Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression. J Cell Biochem. 2009;106(4):589-98.)
Moisturisers tend to be creamier and more viscous, therefore Revision Skincare® recommend applying moisturisers after their lighter antioxidant-based products or serums. Revision Skincare® suggest that if you are only using their products, you can mix the products together into a “cocktail” and apply simultaneously in one application.
This is very dependent on the antioxidant product. Most antioxidant products contain L-Ascorbic Acid which tend to have an extremely low pH.
Revision Skincare® advises patients to wait 10-15 minutes before applying other products. One of the reasons that the scientists at Revision Skincare® decided to use Tetrahexyldecyl Ascorbate (THD) was because THD Ascorbate has been shown to boost intracellular levels of L-Ascorbic Acid and does not present pH issues as described above.
Yes, sunscreens should always be placed last on the skin as this will allow for the most optimal protection from UV radiation (HEV/IR). The goal of a sunscreen is to remain on the top layer of the skin which allows for optimal absorption of UV radiation and this is the case whether it is a chemical or physical sunscreen.
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Clinical Studies
Revision Skincare® is supported by clinical studies that prove the effectiveness of their products and ingredients, giving practitioners the confidence to prescribe and recommend them. Explore the science behind the success.
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