CHANGING THE GAME
REVISION SKINCARE® WAS FOUNDED TO CHANGE THE WAY PROFESSIONAL SKINCARE RESULTS ARE ACHIEVED
Believing that youthful-looking skin can be accomplished without compromising the skin’s long-term health, Revision Skincare® pioneered the use of bio-available peptides, which help combat visible signs of ageing, and formulates all of its products with prebiotic technology to harness skin’s natural microbiome.
Their unique formulation philosophy is leading the way for better treatment methods and challenging traditional approaches to deliver powerful results.
With products validated by doctors, Revision Skincare® proudly serves skincare professionals around the world to help Achieve Healthy, Beautiful Skin™.
THE SCIENTISTS AT REVISION SKINCARE® POUR THEIR HEARTS, AS WELL AS THEIR SCIENTIFIC EXPERTISE, INTO MAKING REVISION SKINCARE® PRODUCTS
Revision Skincare® scientists are driven by a profound passion to develop product formulations that deliver real skincare benefits.
They follow the highest standards of ingredient selection with innovative processes that retain the ingredients' purity and strength.
Their proprietary formulations ensure maximum stability and optimum results. All Revision Skincare® products are formulated with scrupulous attention to detail and an uncompromising commitment to providing the very best.
ACHIEVE HEALTHY, BEAUTIFUL SKIN™
FOR OVER 30 YEARS, REVISION SKINCARE® PROVIDED PHYSICIANS WITH CLINICALLY-PROVEN, HIGH-PERFORMING SKINCARE PRODUCTS
Using only the purest, most efficacious ingredients, the line of Revision Skincare® products was formulated to provide targeted solutions for enhancing the skin’s appearance and reducing signs of ageing for optimum results. Revision Skincare® believe that you cannot take shortcuts to healthy, beautiful skin.
That is why they own every moment of a product’s life until it reaches the end consumer. Great lengths have been pursued to craft and re-craft all their formulations to perfection.
Find out more about Revision Skincare® on our consumer website:
How does THD-Ascorbate convert to L-ascorbic acid?
THD Ascorbate is an ester of Vitamin C that permeates the skin and is converted to ascorbic acid in the skin by esterase. This theory is supported by several tests including using a 3D skin model to perform an evaluation of a formulation containing 10% THD Ascorbate.
The stratum corneum of the 3D skin model was treated for a 48 hour period and a HPLC analysis was then performed. The results show that the formulation containing THD Ascorbate penetrated and was converted to ascorbic acid in the 3D skin model.
(Ochiai Y, Kaburagi S, Obayashi K, et al. A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties. J Dermatol Sci. 2006;44(1):37-44.)
Another test shows that THD Ascorbate permeates the hydrophobic plasma membrane and is converted to ascorbic acid in NHDF fibroblasts. The test was conducted in parallel with ascorbic acid and THD Ascorbate enhanced intracellular ascorbic acid levels more so than ascorbic acid itself. It is assumed that the accumulation of ascorbic acid occurred through esterolytic conversion of the THD Ascorbate.
(Xiao L, Kaneyasu K, Saitoh Y, Terashima Y, Kowata Y, Miwa N. Cytoprotective effects of the lipoidic-liquiform pro-vitamin C tetra-isopalmitoyl-ascorbate (VC-IP) against ultraviolet-A ray-induced injuries in human skin cells together with collagen retention, MMP inhibition and p53 gene repression. J Cell Biochem. 2009;106(4):589-98.)
If patients need a moisturiser, when in their routine should they be applying it and why?
Moisturisers tend to be creamier and more viscous, therefore Revision Skincare® recommend applying moisturisers after their lighter antioxidant-based products or serums. Revision Skincare® suggest that if you are only using their products, you can mix the products together into a “cocktail” and apply simultaneously in one application.
Is there any risk that antioxidants can deactivate other products?
This is very dependent on the antioxidant product. Most antioxidant products contain L-Ascorbic Acid which tend to have an extremely low pH.
Revision Skincare® advises patients to wait 10-15 minutes before applying other products. One of the reasons that the scientists at Revision Skincare® decided to use Tetrahexyldecyl Ascorbate (THD) was because THD Ascorbate has been shown to boost intracellular levels of L-Ascorbic Acid and does not present pH issues as described above.
Is it correct for me to tell my patients to put on sunscreen last?
Yes, sunscreens should always be placed last on the skin as this will allow for the most optimal protection from UV radiation (HEV/IR). The goal of a sunscreen is to remain on the top layer of the skin which allows for optimal absorption of UV radiation and this is the case whether it is a chemical or physical sunscreen.
What is unique about Revox™ Line Relaxer?
Revox™ Line Relaxer features eight bioavailable peptides while Revox™ 7 has seven. However, the technologies are different. Both products reduce the intensity of expression lines by inhibiting acetylcholine release from the nerve endings to the muscle, but Revox™ Line Relaxer features breakthrough, patent-pending Line Relax™ Technology that more effectively helps relax lines and wrinkles.
It does this by utilising 5 neuromodulating bioavailable peptides plus Gamma-Aminobutyric Acid (GABA) to also work at the epidermal level, mitigating the release of acetylcholine from the keratinocyte which helps reduce its dissemination throughout the facial skin and is more effective at relaxing. Both products contain three bioavailable reparative peptides, but Revox™ Line Relaxer has the addition of two highly efficacious botanical extracts as part of a Dermal Support Blend that stimulates four types of collagen, while Revox™ 7 formula stimulates two types of collagen.
Also, Revox™ Line Relaxer activates Integrin synthesis while inhibiting MMP production. Revox™ Line Relaxer contains additional ingredients for more advanced benefits such as Hyaluronic Acid, Inulin and Arnica Montana Flower Extract.