Intensive Pigment Corrector

Help your patients improve the appearance of skin hyperpigmentation

Cyspera® is a biological depigmenting treatment for hyperpigmentation concerns.

Hyperpigmentation is a common skin condition in which some areas of the skin become darker in colour than the surrounding skin. Hyperpigmentation occurs when an excess of melanin is produced by melanocytes, the pigment cells, which are moved up to the skin’s surface.

Hyperpigmentation can be caused by inflammation, hormonal stress, sun damage, or other skin injuries. People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure.

 The active ingredient is cysteamine. Naturally present in human skin cells, cysteamine regulates melanin synthesis in the skin. It has been formulated to work as an effective topical treatment, Cyspera®.

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Clinically Proven Results

Cyspera® is a biological molecule that reduces melanin pigments in human skin. It helps remove brown spots, treats pigmented marks and produces an even and light skin complexion.

Significant depigmenting effectiveness. Highly biocompatible and well tolerated. Non-cytotoxic, non-mutagenic, non-carcinogenic Superior benefit/risk ratio compared to hydroquinone –and all other alternative. 

67% melanin pigment reduction in hyperpigmented areas.

92% of users noticed moderate to significant improvements.

Ref Mansouri, P.; Farshi, S.; Hashemi, Z.; Kasraee, B. (2015).”Evaluation of the efficacy of cysteamine 5% cream in the treatment of epidermal melasma: a randomized double-blind placebo-controlled trial”. The British Journal of Dermatology. 173 (1): 209–217 Wang Y & Marini L “A review on the efficacy and safety of L-cysteamine as a skin depigmenting agent. AAD 2018, ePoster 7687

For optimal results

The use of high SPF sunblock is highly recommended year-round for sun damage protection.

Cyspera® is not a photosensitizer. It can be applied regardless of the sun intensity and on any skin phototypes. Cyspera® contains ingredients to reduce hyperpigmentation. Undesirable effects may occur ; learn more under the “Non-significant Undesirable Effects“ section.


Intensive phase: Once per day for 16 weeks Maintenance phase: Twice-weekly, once per day


Do not wash the skin before application. If necessary to wash, wait for 1 hour before application.

15 mins

Apply a thin layer on the skin (a warming sensation or mild tingling may occur and last up to 30 minutes). Leave on for 15 minutes.

Wash Off

Remove by washing the area with a gentle face cleanser. Gently pat your face dry.


Moisturise the area. Maintain skin hydration during the day.